An unusual case of intestinal leiomyositis in a Bernese mountain dog = Ein ungewöhnlicher Fall von Darmleiomyositis beim Berner Sennenhund
Articolo
Data di Pubblicazione:
2015
Citazione:
An unusual case of intestinal leiomyositis in a Bernese mountain dog = Ein ungewöhnlicher Fall von Darmleiomyositis beim Berner Sennenhund / P. Gianella, M. Tecilla, C. Bellino, R. Buracco, M. Martano, R. Zanatta, A. Cagnasso, A. D'Angelo. - In: SCHWEIZER ARCHIV FUR TIERHEILKUNDE. - ISSN 0036-7281. - 157:10(2015 Oct), pp. 563-567. [10.17236/sat00038]
Abstract:
A 1-year-old, female Bernese mountain dog was presented to the Veterinary Teaching Hospital of Turin University with a 3-month history of weight loss, intermittent anorexia, vomiting, constipation, and abdominal distension. Full-thickness biopsies from the stomach, duodenum, jejunum and ileum were collected for histological and immunohistochemical examination. Microscopic lesions displayed severe diffuse degeneration and loss of leiomyocytes, with lymphocytic leiomyositis, fibroplasia, angiogenesis, severe diffuse neuronal atrophy, and ganglioneuritis in the myenteric (Auerbach's) plexus. A diagnosis of chronic idiopatic intestinal pseudo-obstruction was made. Response to immunosuppressive therapy was poor and the dog was humanely euthanized. Unique findings were mononuclear infiltration composed predominantly of B-cell, angiogenesis and weak immunoreactivity for neuron-specific enolase.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
animals; dog diseases; dogs; euthanasia, animal; fatal outcome; female; immunohistochemistry; immunosuppression; intestinal pseudo-obstruction; treatment failure; Hund; Pseudoobstruktion; Darm; Leiomyositis; B-Lymphozyten
Elenco autori:
P. Gianella, M. Tecilla, C. Bellino, R. Buracco, M. Martano, R. Zanatta, A. Cagnasso, A. D'Angelo
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