Gold(I)-Catalyzed Synthesis of Tetrahydrocarbazoles via Cascade [3,3]-Propargylic Rearrangement/[4+2] Cycloaddition of Vinylindoles and Propargylic Esters
Articolo
Data di Pubblicazione:
2016
Citazione:
Gold(I)-Catalyzed Synthesis of Tetrahydrocarbazoles via Cascade [3,3]-Propargylic Rearrangement/[4+2] Cycloaddition of Vinylindoles and Propargylic Esters / V. Pirovano, E. Arpini, M. Dell’Acqua, R. Vicente, G. Abbiati, E. Rossi. - In: ADVANCED SYNTHESIS & CATALYSIS. - ISSN 1615-4150. - 358:3(2016), pp. 403-409.
Abstract:
A gold(I)-catalyzed cascade [3,3]-propargylic
rearrangement and [4+2] cycloaddition reaction
of 2-vinylindoles with propargylic esters is reported.
The reaction leads to the synthesis of highly substituted
tetrahydrocarbazole derivatives in high yields
and diasteroselectivities. Furthermore, a preliminary
screening for an asymmetric version of this reaction
is described.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
cycloaddition; gold; nitrogen heterocycles; rearrangement
Elenco autori:
V. Pirovano, E. Arpini, M. Dell’Acqua, R. Vicente, G. Abbiati, E. Rossi
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