General anesthesia reduces the information exchange between heart and circulation
Contributo in Atti di convegno
Data di Pubblicazione:
2015
Citazione:
General anesthesia reduces the information exchange between heart and circulation / A. Porta, V. Bari, A. Marchi, B. De Maria, V. Pistuddi, M. Ranucci (PROCEEDINGS OF THE ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY). - In: 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)[s.l] : IEEE, 2015. - ISBN 9781424492718.-4029 (( Intervento presentato al 37. convegno EMBS tenutosi a Milano nel 2015 [10.1109/EMBC.2015.7319278].
Abstract:
The study demonstrates the ability of an information-theoretic measure, such as the transfer entropy (TE), in detecting the depression of the cardiac baroreflex control and circulatory-cardio mechanical feedforward link during propofol-induced general anesthesia. TE was computed from spontaneous variability of heart period (HP) and systolic arterial pressure (SAP) in patients undergoing coronary artery bypass graft (CABG). TE from SAP to HP and from HP to SAP were evaluated by accounting for the confounding effect of respiration (R) affecting both HP and SAP (i.e. TESAP→HP-R and TEHP→SAP-R respectively). Both TESAP→HP-R and TEHP→SAP-R decreased during general anesthesia, thus suggesting that the strength of the causal relation diminished over both arms of the closed loop HP-SAP control. The squared coherence function between HP and SAP confirmed the decreased HP-SAP coupling during general anesthesia, even though it could not distinguish directionality.
Tipologia IRIS:
03 - Contributo in volume
Elenco autori:
A. Porta, V. Bari, A. Marchi, B. De Maria, V. Pistuddi, M. Ranucci
Link alla scheda completa:
Titolo del libro:
2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)