Data di Pubblicazione:
2014
Citazione:
Pain pharmacology : focus on opioids / D. Fornasari. - In: CLINICAL CASES IN MINERAL AND BONE METABOLISM. - ISSN 1724-8914. - 11:3(2014 Sep), pp. 165-168. [10.1138/ccmbm/2014.11.3.165]
Abstract:
The incidence of chronic pain is estimated to be 20-25% worldwide. Although major improvements in pain control have been obtained, more than 50% of the patients reports inadequate relief. It is accepted that chronic pain, if not adequately and rapidly treated, can become a disease in itself, often intractable and maybe irreversible. This is mainly due to neuroplasticity of pain pathways. In the present review I will discuss about pain depicting the rational for the principal pharmacological interventions and finally focusing on opioids, that represent a primary class of drug to treat pain.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Chronic pain; Multi-target pharmacology; Opioids; Tapentadol
Elenco autori:
D. Fornasari
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