Preparation of quinolizidinyl derivatives of phenothiazine and thioxanthene of pharmacological interest
Articolo
Data di Pubblicazione:
1989
Citazione:
Preparation of quinolizidinyl derivatives of phenothiazine and thioxanthene of pharmacological interest / A. Sparatore, V. Boido, F. Sparatore. - In: IL FARMACO. - ISSN 0014-827X. - 44:12(1989), pp. 1193-1203.
Abstract:
Quinolizidinyl derivs. of phenothiazine and thioxanthene, e.g. I, were prepd. to study the effects on the uptake and release of some neurotransmitter in rat brain synaptosomes. In one attempt to prep. the homolupinanoylphenothiazine from homolupinanoyl chloride a compd. was obtained, to which the structure of 2,4-diquinolizidinylcyclobutan-1,3-dione (II) was assigned. When heated with acids this compd. gives rise to the dilupinyl ketone, also obtained from cyanolupinane and lupinylmagnesium chloride.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
quinolizidinyl derivatives ; phenothiazine derivatives ; thioxanthene derivatives ; dilupinylketone
Elenco autori:
A. Sparatore, V. Boido, F. Sparatore
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