Data di Pubblicazione:
1998
Citazione:
Worsening in seizure frequency and severity in relation to folic acid administration / L. Guidolin, A. Vignoli, R. Canger. - In: EUROPEAN JOURNAL OF NEUROLOGY. - ISSN 1351-5101. - 5:3(1998 May), pp. 301-303.
Abstract:
We report a case of increase in seizure frequency and severity in a 26-year-old woman receiving folic acid at a dosage of 0.8 mg/day. She had symptomatic partial epilepsy with simple and complex seizures treated with carbamazepine. She was planning pregnancy and we prescribed folic acid for prevention of neural-tube defects. In the next few days she had a generalized tonic-clonic seizure for the first time and a significant increase in seizure frequency. Because of the temporal relation between the seizure worsening and the administration of folic acid, we hypothesize a role of folic acid in provoking seizures, as has been reported in the literature.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Epilepsy; Folic acid; Pregnancy
Elenco autori:
L. Guidolin, A. Vignoli, R. Canger
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