Effects of slow deep breathing at high altitude on oxygen saturation, pulmonary and systemic hemodynamics
Articolo
Data di Pubblicazione:
2012
Citazione:
Effects of slow deep breathing at high altitude on oxygen saturation, pulmonary and systemic hemodynamics / G. Bilo, M. Revera, M. Bussotti, D. Bonacina, K. Styczkiewicz, G. Caldara, A. Giglio, A. Faini, A. Giuliano, C. Lombardi, K. Kawecka-Jaszcz, G. Mancia, P. Agostoni, G. Parati. - In: PLOS ONE. - ISSN 1932-6203. - 7:11(2012 Nov 12), pp. e49074.1-e49074.7. [10.1371/journal.pone.0049074]
Abstract:
Slow deep breathing improves blood oxygenation (SpO2) and affects hemodynamics in hypoxic patients. We investigated the ventilatory and hemodynamic effects of slow deep breathing in normal subjects at high altitude. We collected data in healthy lowlanders staying either at 4559 m for 2-3 days (Study A; N = 39) or at 5400 m for 12-16 days (Study B; N = 28). Study variables, including SpO2 and systemic and pulmonary arterial pressure, were assessed before, during and after 15 minutes of breathing at 6 breaths/min. At the end of slow breathing, an increase in SpO2 (Study A: from 80.2±7.7% to 89.5±8.2%; Study B: from 81.0±4.2% to 88.6±4.5; both p<0.001) and significant reductions in systemic and pulmonary arterial pressure occurred. This was associated with increased tidal volume and no changes in minute ventilation or pulmonary CO diffusion. Slow deep breathing improves ventilation efficiency for oxygen as shown by blood oxygenation increase, and it reduces systemic and pulmonary blood pressure at high altitude but does not change pulmonary gas diffusion.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Altitude; Respiration; Carbon Dioxide; Exercise; Female; Hemodynamics; Humans; Italy; Lung; Male; Nepal; Oxygen; Partial Pressure; Pulmonary Ventilation
Elenco autori:
G. Bilo, M. Revera, M. Bussotti, D. Bonacina, K. Styczkiewicz, G. Caldara, A. Giglio, A. Faini, A. Giuliano, C. Lombardi, K. Kawecka Jaszcz, G. Mancia, P. Agostoni, G. Parati
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