Specific and common antigenic determinants of Candida albicans isolates detected by monoclonal antibody
Articolo
Data di Pubblicazione:
1986
Citazione:
Specific and common antigenic determinants of Candida albicans isolates detected by monoclonal antibody / L. Polonelli, G. Morace. - In: JOURNAL OF CLINICAL MICROBIOLOGY. - ISSN 0095-1137. - 23:2(1986 Feb), pp. 366-368.
Abstract:
We isolated a hybridoma cell line which produced monoclonal antibody to one determinant of an exoantigen of Candida albicans. The immunoglobulin G antibody product was characterized by using a Western blot technique and was used for a serological analysis of numerous homologous and heterologous yeast isolates. Based on specific immunologic determinants, C. albicans strains were identified and clustered into five groups. The monoclonal antibodies were effective reagents for identifying and serotyping our C. albicans isolates; they have potential application in the epidemiology of yeast infections.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
animals ; antibodies, monoclonal ; antigens, fungal ; candida albicans ; epitopes ; fungal proteins ; hybridomas ; immunoglobulin G ; mice ; mice, inbred BALB C ; serotyping ; species specificity
Elenco autori:
L. Polonelli, G. Morace
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