Data di Pubblicazione:
2005
Citazione:
Metodiche di immagine per valutare la progressione della placca aterosclerotica / P. Raggi, A. Bellasi. - In: ITALIAN HEART JOURNAL. SUPPLEMENT. - ISSN 1129-4728. - 6:8(2005 Aug), pp. 481-488.
Abstract:
Cardiovascular disease is the first cause of morbidity and mortality for both men and women in
developed countries. Tracking the progression of the atherosclerotic plaque appears to be an effective way to predict modification of risk in individual patients. Quantitative coronary angiography was initially proposed as a method of choice to assess coronary disease progression. With this methodology it was possible to demonstrate a strong association of plaque regression with reduction in adverse cardiovascular outcomes. More recently, the focus of research has turned to the development of noninvasive modalities to image the atherosclerotic plaque in its preclinical stages and to evaluate the effectiveness of preventive therapies with sequential imaging. The ease of performance of these tests enabled their use as intermediate endpoints in clinical trials to test new strategies to treat atherosclerosis.
If proven successful, these imaging tools may allow a reduction in size and duration of clinical trials
with a substantial cost benefit for society.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Atherosclerosis; Calcium score; Magnetic resonance; Plaque
Elenco autori:
P. Raggi, A. Bellasi
Link alla scheda completa: