Data di Pubblicazione:
2013
Citazione:
Glycemic control in the clinical management of diabetic patients / A. Mosca, A. Lapolla, P. Gillery. - In: CLINICAL CHEMISTRY AND LABORATORY MEDICINE. - ISSN 1434-6621. - 51:4(2013), pp. 753-766. [10.1515/cclm-2012-0594]
Abstract:
In clinical practice, glycemic control is generally assessed by measuring and interpreting glycated hemoglobin levels, however, this test should be run under standardized conditions. We focus here on the crucial steps to ensure IFCC standardized HbA 1c results, pointing out several residual weak points, mostly relating to the laboratory end-user (calibration, quality control materials, and EQAS). We also review the use of HbA 1c for diagnosing diabetes and the various indicators useful for assessing glucose variability because in some cases they seem to represent a patient ' s glucose profile more accurately than one-off HbA 1c assays. Finally, the potential utility of glycated albumin and the glycation gap, the costs involved and the laboratory management issues are briefly discussed.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Glycated albumin; Glycated hemoglobin; Glycation gap; HbA 1c glucose variability; Standardization
Elenco autori:
A. Mosca, A. Lapolla, P. Gillery
Link alla scheda completa: