Data di Pubblicazione:
2011
Citazione:
Safety issues with ethanol as an excipient in drugs intended for pediatric use / G.V. Zuccotti, V. Fabiano. - In: EXPERT OPINION ON DRUG SAFETY. - ISSN 1474-0338. - 10:4(2011 Jul), pp. 499-502. [10.1517/14740338.2011.565328]
Abstract:
Ethanol is commonly used as an excipient in the manufacture of medicines, including the ones intended for administration in children. However, ethanol cannot be considered an inert substance; on the contrary, its use in pharmaceutical preparations is associated with safety issues. Newborns, infants and children are not able to metabolize ethanol as efficiently as adults; as a consequence, they may be at higher risk of both acute and chronic alcohol-related toxicities.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
children; drugs; ethanol; excipients
Elenco autori:
G.V. Zuccotti, V. Fabiano
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