Unusual organization of the 5S ribosomal spacer in Dirofilaria repens : absence of a canonical spliced leader 1 sequence
Articolo
Data di Pubblicazione:
2000
Citazione:
Unusual organization of the 5S ribosomal spacer in Dirofilaria repens : absence of a canonical spliced leader 1 sequence / G. Favia, C. Bazzocchi, G. Cancrini, C. Genchi, C. Bandi. - In: PARASITOLOGY RESEARCH. - ISSN 0932-0113. - 86:6(2000 Jun), pp. 497-499.
Abstract:
Comparing the 5S ribosomal RNA spacer of Dirofilaria repens and D. immitis, we found that in D. repens PCR generates two amplification products. In both products, the putative spliced leader 1 sequences (SL1) show some nucleotide substitutions compared to the canonical SL1 sequence of nematodes. SL1 is a short sequence transferred to the 5' end of most messenger RNAs through a trans-splicing reaction. All the other filariae studied thus far amplify a single fragment showing a canonical SL1 sequence. D. repens appears thus peculiar.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
G. Favia, C. Bazzocchi, G. Cancrini, C. Genchi, C. Bandi
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