Sericine exhibit ROS-scavenging, anti-tyrosinase, anti-elestase, and in vitro immunomodulatory activities
Articolo
Data di Pubblicazione:
2013
Citazione:
Sericine exhibit ROS-scavenging, anti-tyrosinase, anti-elestase, and in vitro immunomodulatory activities / T. Chlapanidas, S. Faragò, G. Lucconi, S. Perteghella, M. Galuzzi, M. Mantelli, M.A. Avanzi, M.C. Tosca, M. Marazzi, D. Vigo, M.L. Torre, M. Faustini. - In: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. - ISSN 0141-8130. - 58(2013 Mar 27), pp. 47-56.
Abstract:
Some biological properties of Bombyx mori sericins from twenty strains were investigated, fourteen fed with artificial diet, two with fresh mulberry leaves and four with both diets. Sericin exhibited ROS-scavenging, anti-tyrosinase and anti-elastase properties, the strain significantly influenced these properties, while diet only influenced the anti-tyrosinase activity. Sericins were clustered into 5 groups and one sericin from each group was further studied: sericins showed anti-proliferative activity on in vitro stimulated peripheral blood mononuclear cells; some strains decreased in vitro secretion of IFNγ, while no effects were observed on TNFα and IL10 release. Therefore, a mixture of sericins extracted from the most promising strains may be useful for dermatological and cosmetic use.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Anti-elastase activity; Anti-IFNγ activity; Anti-proliferative activity; Anti-tyrosinase activity; ROS-scavenging activity; Sericin
Elenco autori:
T. Chlapanidas, S. Faragò, G. Lucconi, S. Perteghella, M. Galuzzi, M. Mantelli, M.A. Avanzi, M.C. Tosca, M. Marazzi, D. Vigo, M.L. Torre, M. Faustini
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