Hydroarylation of substituted norbornene amino acids : studies on long-range stereo-electronic effects on the regioselectivity of the addition
Articolo
Data di Pubblicazione:
2012
Citazione:
Hydroarylation of substituted norbornene amino acids : studies on long-range stereo-electronic effects on the regioselectivity of the addition / A. Ruffoni, A. Casoni, M.L. Gelmi, S. Pellegrino, F. Clerici. - In: CURRENT ORGANIC CHEMISTRY. - ISSN 1385-2728. - 16:22(2012), pp. 2724-2738. [10.2174/138527212804004472]
Abstract:
Studies on the Pd-catalyzed hydroarylation reaction of a library of differently substituted norbornene amino acid derivatives with numerous halogenoarenes are described. The effect on the regiochemistry of remote substituents, arylating agents and reaction conditions was considered. The reaction occurred with moderate to good yields and a moderate level of regioselectivity being the coupling at C-5 favorite.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
bicyclic alkenes; catalysis; hydroarylations; norbornene amino acid derivatives; Pd-catalyzed reactions; regioselectivity
Elenco autori:
A. Ruffoni, A. Casoni, M.L. Gelmi, S. Pellegrino, F. Clerici
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