Current status of salvage robot-assisted laparoscopic prostatectomy for radiorecurrent prostate cancer
Articolo
Data di Pubblicazione:
2012
Citazione:
Current status of salvage robot-assisted laparoscopic prostatectomy for radiorecurrent prostate cancer / B. Rocco, G. Cozzi, M.G. Spinelli, A. Grasso, D. Varisco, R.F. Cohelo, V.R. Patel. - In: CURRENT UROLOGY REPORTS. - ISSN 1527-2737. - 13:3(2012), pp. 195-201. [10.1007/s11934-012-0245-1]
Abstract:
Radiation therapy (RT) is one of the treatment options for prostate cancer (PCa). Transperineal low-dose rate brachytherapy (BT) is another safe and effective technique for low-risk PCa. Recurrence after RT for localized PCa can be defined by a PSA value of 2 ng/mL above the nadir after RT, and biochemical recurrence (BCR) rate after RT is 40-60 %. In case of radiorecurrent PCa, treatment options include salvage radical prostatectomy (RP), cryo-therapy, high-intensity focused ultrasound (HIFU), and salvage BT. Only salvage RP has cancer control results for over 10-year follow-up in a substantial portion of patients (30-40 %). However, salvage RP is technically demanding, and experienced surgeons are needed; in fact, RT-induced cystitis, fibrosis, and tissue plane obliteration can lead to significant complications, such as rectal injuries, anastomot-ic stricture, and urinary incontinence. This review describes indications, oncologic and functional outcomes, surgical techniques, and complications of salvage robot-assisted RP.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Brachytherapy; Endourology; Prostate cancer; Radiation failure; Radiation therapy; Radiorecurrent prostate cancer; Recurrence; Salvage robot-assisted laparoscopic prostatectomy; sRALP; Surgery
Elenco autori:
B. Rocco, G. Cozzi, M.G. Spinelli, A. Grasso, D. Varisco, R.F. Cohelo, V.R. Patel
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