OXY-SCORE : a global index to improve evaluation of oxidative stress by combining pro- and antioxidant markers
Capitolo
Data di Pubblicazione:
2010
Citazione:
OXY-SCORE : a global index to improve evaluation of oxidative stress by combining pro- and antioxidant markers / F. Veglia, V. Cavalca, E. Tremoli - In: Advanced Protocols in Oxidative Stress II / [a cura di] D. Armstrong. - [s.l] : Humana Press, 2010. - ISBN 9781607614104. - pp. 197-213
Abstract:
Our group recently proposed OXY-SCORE, a summary index of oxidative stress, computed by combining plasma free and total malondialdehyde (F- and T-MDA), glutathione in disulphide/reduced forms (GSSG/GSH), α- and γ-tocopherol (TH), urine isoprostanes (iPF2α-III) levels, and plasma individual antioxidant capacity. Here, we describe the methods for the determination of the analytes and for the computation of the scores. We also report the results of two studies testing the performances of OXY-SCORE, and showing its value in assessing the oxidative status of cardiovascular patients and healthy subjects.
Tipologia IRIS:
03 - Contributo in volume
Keywords:
Coronary artery disease; Glutathione; Isoprostanes; Malondialdehyde; Oxidative stress; Vitamin E
Elenco autori:
F. Veglia, V. Cavalca, E. Tremoli
Link alla scheda completa:
Titolo del libro:
Advanced Protocols in Oxidative Stress II