T-lymphocyte cholecystokinin-8 and beta-endorphin concentrations in eating disorders : I. Anorexia nervosa
Articolo
Data di Pubblicazione:
1995
Citazione:
T-lymphocyte cholecystokinin-8 and beta-endorphin concentrations in eating disorders : I. Anorexia nervosa / F. Brambilla, M. Brunetta, A. Peirone, G. Perna, P. Sacerdote, B. Manfredi, A.E. Panerai. - In: PSYCHIATRY RESEARCH. - ISSN 0165-1781. - 59:1-2(1995 Nov 29), pp. 43-50.
Abstract:
Baseline concentrations of cholecystokinin-8 (CCK-8) and beta-endorphin (beta-EP) were measured in T-lymphocytes from 33 restricting patients with anorexia nervosa (AN-R), 23 binging/purging patients with anorexia nervosa (AN-BP), and 24 healthy volunteers. CCK-8 basal values were significantly lower and beta-EP values significantly higher in AN-R and AN-BP patients than in normal volunteers. Levels of the peptides were measured three more times during a 4-month combined cognitive-behavioral/psychopharmacological treatment (nortriptyline or fluoxetine in AN-R, fluoxetine or amineptine in AN-BP). CCK-8 values fluctuated (nonsignificantly) during each treatment, while beta-EP values decreased (to a significant degree only in fluoxetine-treated AN-R patients).
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Amineptine; Anorexia nervosa; Fluoxetine; Nortriptyline; Peptides
Elenco autori:
F. Brambilla, M. Brunetta, A. Peirone, G. Perna, P. Sacerdote, B. Manfredi, A.E. Panerai
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