Data di Pubblicazione:
1989
Citazione:
2-substituted derivatives of benzimidazole inhibiting gastric acid secretion in rats / A. Pinelli, S. Trivulzio, L. Malvezzi, G. Rossoni, L. Beretta. - In: ARZNEIMITTEL-FORSCHUNG. - ISSN 0004-4172. - 39:4(1989), pp. 467-469.
Abstract:
Benzimidazole and its 2-derivatives with amino, carbamonitrile, urea, and guanidine groups have been tested for their activity on gastric secretory process. The carbamonitrile-, urea-, and guanidine compounds decrease gastric acid secretion, basal and stimulated with histamine or betazole, in Shay-rats and depress the guinea pig auricle activity stimulated by betazole. The results suggest that the studied 2-substituted benzimidazole compounds exhibit anti H2-histamine activity.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Benzimidazoles ; Gastric Acidity Determination
Elenco autori:
A. Pinelli, S. Trivulzio, L. Malvezzi, G. Rossoni, L. Beretta
Link alla scheda completa: