Data di Pubblicazione:
2011
Citazione:
IVF and endometriosis-related symptom progression : insights from a prospective study / L. Benaglia, E. Somigliana, G. Santi, C. Scarduelli, G. Ragni, L. Fedele. - In: HUMAN REPRODUCTION. - ISSN 0268-1161. - 26:9(2011 Sep), pp. 2368-2372.
Abstract:
BACKGROUND: A possible and neglected concern in women with endometriosis undergoing IVF is the potential risk of progression of the disease. We set up a prospective study mainly aimed at evaluating the impact of IVF on endometriosis-related symptoms.
MATERIALS AND METHODS: Women with surgical or echographic diagnosis of endometriosis and selected for IVF were included. In the month preceding the IVF attempt and at a second evaluation 3-6 months after the cycle, women who did not get pregnant underwent clinical assessment and transvaginal ultrasonography. Each patient was requested to complete a questionnaire on the presence, severity and modifications of endometriosis-related symptoms before and after the IVF cycle.
RESULTS: Overall, 64 patients completed the study protocol. The Biberoglu-Behrman Scores and the Verbal Rate Scales for dysmenorrhea, dispareunia and chronic pelvic pain did not worsen after the procedure. Other endometriosis-related symptoms also did not change. There was no modification in size and number of endometriomas and deep peritoneal nodules. The number (%) of women reporting general improvement and worsening were 14 (22%) and 7 (11%), respectively.
CONCLUSIONS: IVF does not expose women to a consistent risk of endometriosis-related symptoms progression.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Endometriosis; endometriosis-related symptoms; IVF
Elenco autori:
L. Benaglia, E. Somigliana, G. Santi, C. Scarduelli, G. Ragni, L. Fedele
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