Data di Pubblicazione:
1978
Citazione:
Detection of two endorphin-like peptides in nucleus caudatus / H.T.T Yang, W. Fratta, J.S. Hong, A.M. Di Giulio, E. Costa. - In: NEUROPHARMACOLOGY. - ISSN 0028-3908. - 17:6(1978), pp. 433-438. [10.1016/0028-3908(78)90023-0]
Abstract:
Two endorphin-like peptides with molecular weight larger than [met5]-enkephaiin were detected in bovine caudate. They were separated from [met5]-enkephal in by Biogel P-2 column chromatography and detected with a [met5]-enkephaiin antibody which possesses some affinity for endorphins larger than [met5]-enkephaiin but smaller than β-endorphin. Our antibody has some affinity for α-endorphin but we can exclude that the two new peptides are α, β-endorphin or β-lipotropin. It is suggested that in nucleus caudatus the two endorphin-like peptides we have detected may function as precursors of [met5]-enkephalin.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
H.T.T. Yang, W. Fratta, J.S. Hong, A.M. Di Giulio, E. Costa
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