Effect of UVB plus tar therapy on serum levels of interleukin-2 receptors in patients with psoriasis
Articolo
Data di Pubblicazione:
1991
Citazione:
Effect of UVB plus tar therapy on serum levels of interleukin-2 receptors in patients with psoriasis / R. Betti, A. Rosti, A. Lodi, P. L. Bencini, S. Paparelli, G. B. Gazzola, P. Cori, G. A. Moroni, C. Crosti. - In: CLINICAL AND EXPERIMENTAL DERMATOLOGY. - ISSN 0307-6938. - 16:5(1991 Sep), pp. 364-366.
Abstract:
Baseline serum levels of interleukin-2 receptor (IL2R) were measured in 65 patients with active psoriasis. IL2R levels in psoriatic patients were significantly higher than in healthy controls (582.4 +/- 289.23 u/ml vs. 369.64 +/- 111.10 u/ml; P less than 0.05), but did not differ statistically from values found in an atopic dermatitis control group (619.88 +/- 254.27 u/ml). Sex, age and severity of the disease do not affect levels of IL2R. The same IL2R levels were measured in 26 psoriatic patients receiving UVB plus tar therapy. This therapy, continued until clinical remission, lowered IL2R levels to values comparable to controls. This decrease may be due to an immunosuppressive effect of therapy.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Ultraviolet Rays; Dermatitis, Atopic; Psoriasis; Humans; Photochemotherapy; Coal Tar; Adult; Aged; Middle Aged; Receptors, Interleukin-2; Male; Female
Elenco autori:
R. Betti, A. Rosti, A. Lodi, P. L. Bencini, S. Paparelli, G. B. Gazzola, P. Cori, G. A. Moroni, C. Crosti
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