Evaluation of different dietary lipid supplements on oxidatively generated biomarkers in periparturient dairy goats
Contributo in Atti di convegno
Data di Pubblicazione:
2012
Citazione:
Evaluation of different dietary lipid supplements on oxidatively generated biomarkers in periparturient dairy goats / F. Bellagamba, M.L. Busetto, F. Caprino, G. Invernizzi, V.M. Moretti, G. Savoini - In: Proceedings of the 2. International conference on environmental stressors in biology and medicineBologna : Monduzzi, 2012. - ISBN 978-88-7587-643-2. - pp. 1-4 (( Intervento presentato al 2. convegno International Conference on Environmental Stressors in Biology and Medicine tenutosi a Siena nel 2011.
Abstract:
This study aimed at analyzing the impact of different dietary lipid supplements on oxidative stress status in 26 Alpine dairy goats fed with diets just differing in lipid sources: protected fish oil (FO), calcium stearate (ST), and control group (C), without any supplement. Blood samples were collected weekly starting from day 130 of gestation (about 20 days before delivery) until 21 days of lactation. Analytical determination of malondialdehyde (MDA) and 8-oxo-7,8-dihydro-2’-deoxyguanosine (8-oxodGuo) have been carried out in serum samples. Gas chromatographic determination of plasma fatty acids (FAs) was also performed. MDA and 8-oxodGuo resulted both higher in FO group when compared to ST and C group, but not at significant level. Dietary lipid supplements produced remarkable change in plasma FAs and after 21 days of supplementation, 20:5 n-3 (eicosapentaenoic, EPA) and 22:6 n-3 (docosahexaenoic, DHA) in FO group resulted significantly different (P ≤ 0.05) from ST and C groups. The significant increase of EPA in FO diet was assessed right after 7 days of supplementation. Positive and significant (P ≤ 0.05) correlations between some FAs and MDA, and 8-oxodGuo were obtained.
Tipologia IRIS:
03 - Contributo in volume
Keywords:
oxidative stress ; dairy goats ; fish oil ; plasma fatty acids ; 8-oxo-7,8-dihydro-2’-deoxyguanosine ; malondialdehyde
Elenco autori:
F. Bellagamba, M.L. Busetto, F. Caprino, G. Invernizzi, V.M. Moretti, G. Savoini
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Titolo del libro:
Proceedings of the 2. International conference on environmental stressors in biology and medicine