Rigid congeners of arylpyridazinones. IV. Synthesis and activity of derivatives of the new heterocyclic system 9H-indeno[2,1-c]pyridazine
Articolo
Data di Pubblicazione:
1985
Citazione:
Rigid congeners of arylpyridazinones. IV. Synthesis and activity of derivatives of the new heterocyclic system 9H-indeno[2,1-c]pyridazine / G.A. Pinna, M.M. Curzu, M. Loriga, G. Cignarella, D. Barlocco, S. Malandrino. - In: IL FARMACO. EDIZIONE SCIENTIFICA. - ISSN 0430-0920. - 40:12(1985), pp. 979-986.
Abstract:
Representative terms of the new heterocyclic system 9H-indeno[2,1-c]pyridazine have been synthesized. Their antiinflammatory, analgesic and antipyretic activities were evaluated, in order to compare the pharmacological profiles with those of the isomeric series of 5H-indeno[1,2-c]pyridazine previously investigated. The new compounds were, in general, equiactive as analgesic but less active as antiinflammatory and antipyretic agents with respect to their 5H-isomers.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
G.A. Pinna, M.M. Curzu, M. Loriga, G. Cignarella, D. Barlocco, S. Malandrino
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