CNS metastasis in ovarian cancer with microangiopathic hemolytic anemia associated with diffuse intravascular coagulation
Articolo
Data di Pubblicazione:
1988
Citazione:
CNS metastasis in ovarian cancer with microangiopathic hemolytic anemia associated with diffuse intravascular coagulation / E. M. Pogliani, C. Fowst, P. Maffé, A. Marozzi, M. Stefani, E. Polli. - In: TUMORI. - ISSN 0300-8916. - 74:6(1988 Dec 31), pp. 731-6-736.
Abstract:
We present the case of a woman affected by ovarian cancer metastatic to multiple lymph node and the CNS. She was affected by hemorrhagic diathesis with microangiopathic alterations, whereas coagulopathy developed only after some days in coincidence with disease worsening. Our patient is probably one of those in which cancer leads to microangiopathy and coagulopathy by means of a tissue factor-like activity, a common event in mucin secretory tumors. Fibrinolytic activity was also increased in our patient as in others of the same type. The main aspect of this case report is metastasis to the CNS and to other multiple sites, which is quite uncommon in such cancers. We retain that tumor procoagulant activity could have played a role in this phenomenon.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Disseminated Intravascular Coagulation; Brain Neoplasms; Ovarian Neoplasms; Adenocarcinoma, Papillary; Humans; Adult; Anemia, Hemolytic; Female
Elenco autori:
E.M. Pogliani, C. Fowst, P. Maffé, A. Marozzi, M. Stefani, E. Polli
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