Severe hypertension in childhood due to prolonged skin application of a mineralocorticoid ointment
Articolo
Data di Pubblicazione:
1984
Citazione:
Severe hypertension in childhood due to prolonged skin application of a mineralocorticoid ointment / A. Bartorelli, A. Rimondini. - In: HYPERTENSION. - ISSN 0194-911X. - 6:4(1984), pp. 586-588.
Abstract:
We report the case of a 9-year-old boy suffering from exzematous dermatitis who was treated for 6 years with a daily dose of 100 mg of a dermatological ointment containing 9 alpha-fluoroprednisolone-21-acetate. At examination the patient's blood pressure was persistently 230/160 mm Hg and was considered essential in origin after secondary forms of arterial hypertension had been excluded. Treatment with nifedipine and labetalol lowered the blood pressure to 150/100 mm Hg. When we became aware of the dermatological treatment, we advised its discontinuance. In the subsequent 7 days, the blood pressure fell to hypotensive levels (75/40 mm Hg) and then became normal a few days after discontinuance of the antihypertensive therapy. This case suggests that prolonged use of topical steroids, commonly prescribed for skin diseases, may cause hypertension, especially in childhood.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Labetalol; Blood Pressure; Humans; Child; Eczema; Fluprednisolone; Time Factors; Nifedipine; Male; Administration, Topical; Hypertension
Elenco autori:
A. Bartorelli, A. Rimondini
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