The efficacy and safety of gamma-linolenic acid in the treatment of infantile atopic dermatitis
Articolo
Data di Pubblicazione:
1994
Citazione:
The efficacy and safety of gamma-linolenic acid in the treatment of infantile atopic dermatitis / A. Fiocchi, M. Sala, P. Signoroni, G. Banderali, C. Agostoni, E. Riva. - In: JOURNAL OF INTERNATIONAL MEDICAL RESEARCH. - ISSN 0300-0605. - 22:1(1994), pp. 24-32. [10.1177/030006059402200103]
Abstract:
The efficacy and safety of gamma-linolenic acid in the treatment of atopic dermatitis was evaluated. The children (mean age, 11.4 months) with atopic dermatitis (mean duration, 8.56 months) were openly treated with 3 g/day gamma-linolenic acid, for 28 days. Clinical evaluations were carried out every 7 days, and parents were asked to keep a diary, recording details of symptoms of eczema every day. Blood chemistry and immunological tests were done before and after treatment. None of the children showed complete recovery of symptoms. A gradual improvement in erythema, excoriations and lichenification was seen; significant differences were shown for itching (P < 0.01), and the use of antihistamines (P < 0.01). A significant rise in the percentage of circulating CD8 was found. No side-effects were recorded. Dietetic and pharmacological approaches are the basis of the treatment of atopic dermatitis and gamma-linolenic acid appears to be a safe and efficient additional therapy for infants and young children.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
γ-Linolenic acid; Atopic dermatitis; Eczema; Evening primrose oil
Elenco autori:
A. Fiocchi, M. Sala, P. Signoroni, G. Banderali, C. Agostoni, E. Riva
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