Data di Pubblicazione:
1997
Citazione:
Neuropatia motoria multifocale / E. Nobile-Orazio, N. Meucci - In: La sclerosi laterale amiotrofica : Attualità diagnostico-terapeutiche e problematiche assistenziali / [a cura di] M. Porta. - Milano : Guerini Scientifica, 1997. - ISBN 9788881071029. - pp. 149-159 (( convegno La sclerosi laterale amiotrofica: attualità e prospettive terapeutiche tenutosi a Ranica nel 1996.
Abstract:
We describe a patient with a chronic, asymmetric, limb weakness, fasciculations, relatively preserved reflexes, normal cranial nerves and no sensory abnormalities. The symptoms had been progressive over 2 years with a stepwise course, and then stabilized. Electrodiagnostic studies showed the presence of multifocal conduction blocks in motor nerves at sites not prone to compression; by contrast, the sensory conduction studies over the same nerve segments were normal, indicating selective involvement of motor fibers. Serum antibodies to the ganglioside GM1 were absent (ELISA). Treatment with prednisone failed to demonstrate any positive effect; a beneficial response was observed only with immunoglobulin therapy.
Tipologia IRIS:
03 - Contributo in volume
Elenco autori:
E. Nobile-Orazio, N. Meucci
Link alla scheda completa:
Titolo del libro:
La sclerosi laterale amiotrofica : Attualità diagnostico-terapeutiche e problematiche assistenziali