Data di Pubblicazione:
2002
Citazione:
Barium alginate cell-delivery systems : correlation between technological parameters / M.L. Torre, M. Faustini, R. Norberti, L. Maggi, G. Maffeo, U. Conte, D. Vigo. - In: INTERNATIONAL JOURNAL OF PHARMACEUTICS. - ISSN 0378-5173. - 242:1-2(2002), pp. 389-391. [10.1016/S0378-5173(02)00223-5]
Abstract:
The most recent trends for the development of several in vitro cell cultures have been oriented towards the cell
immobilisation in 3-dimensional scaffolds and cell encapsulation. In fact, an important requirement of cell survival is
self-assembly in functional communities, in the presence of an artificial extracellular matrix. In our research, a
previously described technique for spermatozoa encapsulation was applied to obtain capsules loaded with an opaque
agent as a model, and to perform a formulative study. A process variable, barium ion concentration, was correlated
to some capsule properties, such as weight, gel thickness, total and core diameter. Ion concentration can be modified
to obtain capsules with predictable characteristics.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Alginate; Capsule formulation; Cell delivery systems
Elenco autori:
M.L. Torre, M. Faustini, R. Norberti, L. Maggi, G. Maffeo, U. Conte, D. Vigo
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