Data di Pubblicazione:
1994
Citazione:
Parapsoriasis in two children: a clinical, immunophenotypic, and immunogenotypic study / S. Menni, R. Piccinno, L. Crosti, E. Berti. - In: PEDIATRIC DERMATOLOGY. - ISSN 0736-8046. - 11:2(1994 Jun), pp. 151-155.
Abstract:
Parapsoriasis has been described rarely in childhood; a few reports mention this condition as preceding early mycosis fungoides. We report a boy age 15 and a girl age 8 years with different clinical features of parapsoriasis who were followed clinically and histologically for about four years. Immunophenotyping of the skin infiltrate and a T cell receptor gene rearrangement analysis were performed on each. The infiltrate was composed mainly of CD4+ and CD45+ lymphocytes in the first patient and of CD8+ and CD45+ in the second. No T cell receptor gene rearrangements were found. The paucity of knowledge about the evolution of this entity in childhood and its relationship to mycosis fungoides makes follow-up critical. The importance of immunophenotyping and immunogenotyping is particularly stressed.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
S. Menni, R. Piccinno, L. Crosti, E. Berti
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