Data di Pubblicazione:
1991
Citazione:
B16 melanoma response in vivo to photochemotherapy with mitoxantrone and red light / A. Andreoni, G. Canti, G. Fabbrocini, M. Mastrocinque, E. Quarto. - In: CANCER LETTERS. - ISSN 0304-3835. - 61:1(1991 Dec 09), pp. 89-94.
Abstract:
The cytocidal activity of light-activated mitoxantrone in mice bearing B16 melanoma was investigated. Mice inoculated with 10(6) tumor cells on day 0 were i.p. injected with 1 mg/kg body weight of mitoxantrone on days 1, 5 and 9 and exposed to 108 J/cm2 of suitably filtered red light from a halogen lamp on days 2, 6 and 10. The treatment significantly prolonged the median survival time compared to both therapy with mitoxantrone and with red light alone.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Neoplasm Transplantation; Animals; Melanoma, Experimental; Photochemotherapy; Mice, Inbred C57BL; Spectrophotometry; Mice; Light; Mitoxantrone; Male
Elenco autori:
A. Andreoni, G. Canti, G. Fabbrocini, M. Mastrocinque, E. Quarto
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