Synthesis of building blocks of human milk oligosaccharides. Fucosylated derivatives of the lacto- and neolacto-series
Articolo
Data di Pubblicazione:
2002
Citazione:
Synthesis of building blocks of human milk oligosaccharides. Fucosylated derivatives of the lacto- and neolacto-series / B. La Ferla, D. Prosperi, L. Lay, G. Russo, L. Panza. - In: CARBOHYDRATE RESEARCH. - ISSN 0008-6215. - 337:15(2002), pp. 1333-1342.
Abstract:
The synthesis of protected fucosylated derivatives of a Gal beta(1--> 3)GlcNAc and of lactosamine Galbeta(1--> 4)GlcNAc building blocks contained in human milk oligosaccharides is described. Both chemical and enzymatic methods have been exploited for selective protection of the disaccharide. Fucosylation of the appropriate derivatives allowed an easy and relatively short access to different products from common precursors. (C) 2002 Elsevier Science Ltd. All rights reserved.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Building block; Human milk; Lewisx; Lipases; N-Acetyl lactosamine; Oligosaccharide derivatives, synthesis
Elenco autori:
B. La Ferla, D. Prosperi, L. Lay, G. Russo, L. Panza
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