Data di Pubblicazione:
2005
Citazione:
Enzyme-assisted introduction and cleavage of protecting groups in nucleoside chemistry / E. Santaniello, L. Alessandrini, P. Ciuffreda - In: Biocatalysis : chemistry and biochemistry / A. Trincone. - Kerala : Research Sigpost, 2005. - ISBN 81-7736-286-0. - pp. 1-27
Abstract:
Synthetic transformations of natural nucleosides and carbocyclic or acyclic analogues require careful choice of methods for introduction/removal of suitable protecting groups. Problems related to chemo-, regio- and stereoselectivity of such transformations, a particularly relevant aspect in nucleoside chemistry, can be adequately solved using a biocatalytic approach. This chapter will illustrate the state of the art in the enzyme-assisted protection/deprotection procedures either in a hydrolytic mode or taking advantage of reactions that can be carried out in organic solvents by suitable lipases.
Tipologia IRIS:
03 - Contributo in volume
Elenco autori:
E. Santaniello, L. Alessandrini, P. Ciuffreda
Link alla scheda completa:
Titolo del libro:
Biocatalysis : chemistry and biochemistry