Data di Pubblicazione:
1990
Citazione:
Isoelectric focusing herpes simplex virus-gB overlay study in brainstem encephalitis / Martino GV, Grimaldi LM, Franciotta DM, Piccolo G, Brustia R, Minali L, Melzi d'Eril GV.. - In: ACTA NEUROLOGICA SCANDINAVICA. - ISSN 0001-6314. - 82:6(1990 Dec), pp. 364-367.
Abstract:
We report a case of herpetic brainstem encephalitis (HBE) retrospectively diagnosed in an adult patient. Conventional immunovirological studies failed to disclose the etiology of this patient's affection. An isoelectric focusing-antigen overlay (IEF-O) technique showed that the target of one of the four cerebrospinal fluid oligoclonal bands was herpes simplex virus (HSV)-1 glycoprotein B, indicating a specific anti-HSV immunoresponse restricted to the CNS. IEF-O may represent a useful support for in vivo diagnosis of HBE.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
brainstem encephalitis; herpes simplex virus type 1; isoelectric focusing antigen overlay; oligoclonal bands
Elenco autori:
Martino GV, Grimaldi LM, Franciotta DM, Piccolo G, Brustia R, Minali L, Melzi d'Eril GV.
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