Leucocitosi neutrofila estrema in un gatto con adenocarcinoma mammario e metastasi polmonari e spleniche
Contributo in Atti di convegno
Data di Pubblicazione:
2005
Citazione:
Leucocitosi neutrofila estrema in un gatto con adenocarcinoma mammario e metastasi polmonari e spleniche / S. Rossi, A. Giordano, U. Bonfanti, M. Caniatti - In: Atti II Congresso Nazionale AIPVet[s.l] : Associazione Italiana Patologi Veterinari, 2005. (( convegno Congresso Nazionale AIPVet tenutosi a Lodi.
Abstract:
A 8-year old female domestic shorthair cat was brought to a referring veterinarian for coughing and dysorexia. Physical
examination revealed a single nodular mass involving the right caudal mammary gland and a mild dyspnoea: in spite of
these clinical findings, the cat seemed to was well-being. Thoracic radiographs suggested a pulmonary pattern of
metastasis. A complete blood cell count revealed an extreme neutrophilic leukocytosis (297.000/μL) and a mild non
regenerative anaemia. Fine needle aspiration biopsy of pulmonary nodules was consistent with malignant epithelial
neoplasia. One month later, despite therapy, patient’s general condition worsened and the cat was euthanasized.
Necropsy and histopathology revealed a primary adenocarcinoma of the mammary gland and a metastatic involvement
of spleen and both lungs. A bone marrow aspirate showed myeloid hyperplasia and mild granulocytic dysplasia.
Extreme neutrophilic leukocytosis is an uncommon hematological finding which can appear during inflammatory and
infective diseases, nonmyelopoietic neoplasms, or chronic myeloid leukemias. In the present case, based on
signalament, clinico-pathological findings and necropsy, a paraneoplastic extreme neutrophilic leukocytosis was first
suspected.
Tipologia IRIS:
03 - Contributo in volume
Elenco autori:
S. Rossi, A. Giordano, U. Bonfanti, M. Caniatti
Link alla scheda completa:
Titolo del libro:
Atti II Congresso Nazionale AIPVet