Data di Pubblicazione:
1990
Citazione:
Central effect of yohimbine on sexual-behavior in the rat / M. Sala, D. Braida, M.P. Leone, P. Calcaterra, S. Monti, E. Gori. - In: PHYSIOLOGY & BEHAVIOR. - ISSN 0031-9384. - 47:1(1990), pp. 165-173.
Abstract:
A large range of doses of yohimbine (Y) was administered intracerebroventricularly (ICV) (5-100 μg/rat) or intraperitoneally (IP) (0.35-10 mg/kg) to male rats and the effects on sexual, locomotor and general behavior were evaluated. For both routes there was a clear-cut inverted-U effect (stimulating/depressing), calculable as parabolic regressions on the log of administered doses. The maximal stimulating doses (15 μg/rat ICV and 1 mg/kg IP) significantly shortened mount, intromission and ejaculation latencies and the mean interintromission interval. These data indicate the importance of CNS mechanisms in the sexual effect of Y.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Central administration; Rat; Sexual behavior; Yohimbine
Elenco autori:
M. Sala, D. Braida, M.P. Leone, P. Calcaterra, S. Monti, E. Gori
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