Development of new methodologies for the mass spectrometry study of bioorganic macromolecules
Articolo
Data di Pubblicazione:
2003
Citazione:
Development of new methodologies for the mass spectrometry study of bioorganic
macromolecules / S. Cristoni, L. Rossi Bernardi. - In: MASS SPECTROMETRY REVIEWS. - ISSN 0277-7037. - 22:6(2003 Dec), pp. 369-406.
Abstract:
In recent years, mass spectrometry has been increasingly used for the analysis
of various macromolecules of biological, biomedical, and biochemical interest.
This increase has been made possible by two key developments: the advent of
electrospray ionization (ESI) and matrix-assisted laser desorption ionization
(MALDI) sources. The two new techniques produce a significant increase in mass
range and in sensitivity that led to the development of new applications and of
new analyzer designs, software, and robotics. This review, apart from the
description of the status of mass spectrometry in the analysis of bioorganic
macromolecules, is mainly devoted to the illustration of the more recent
promising techniques and on their possible future evolution.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Macromolecular Substances
Oligonucleotides Oligosaccharides Peptides
Proteins
Elenco autori:
S. Cristoni, L. Rossi Bernardi
Link alla scheda completa: