Data di Pubblicazione:
1986
Citazione:
SEXUAL DIMORPHISM IN THE RESPONSE OF THE GABAERGIC SYSTEM TO ESTROGEN ADMINISTRATION / J. PEREZ, I. ZUCCHI, A. MAGGI. - In: JOURNAL OF NEUROCHEMISTRY. - ISSN 0022-3042. - 47:6(1986 Dec), pp. 1798-1803.
Abstract:
Administration of estradiol benzoate to gonadectomized female rats results in up-regulation of CNS gamma-aminobutyric acid (GABA) receptors. The increase of [3H]muscimol binding activity is observed in six of the seven brain areas examined. The same treatment, performed in castrated male or androgenized female rats, induced an increase of [3H]muscimol binding only in the striatum. Evidence is provided suggesting that the dimorphic sensitivity of GABA receptor is not correlated with the difference in spontaneous motor activity reported between male and female rats.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
J. PEREZ, I. ZUCCHI, A. MAGGI
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