Lipase catalysed resolution of (R)- and (S)-1-trimethylsilyl-1-alkyn-3-ols: Useful intermediates for the synthesis of optically active gamma-lactones
Articolo
Data di Pubblicazione:
1997
Citazione:
Lipase catalysed resolution of (R)- and (S)-1-trimethylsilyl-1-alkyn-3-ols: Useful intermediates for the synthesis of optically active gamma-lactones / P. Allevi, P. Ciuffreda, M. Anastasia. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - 8:1(1997), pp. 93-99. [10.1016/S0957-4166(96)00475-2]
Abstract:
Various (R)- and (S)-1-trimethylsilyl-1-alkyn-3-ols, chiral building units useful for the synthesis of biologically active compounds, have been efficiently resolved by enantioselective acetylation mediated by immobilized lipase PS. The resolution is applied to the synthesis of (R)- and (S)-5-octyl-2-(5H)-furanones
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
CHIRAL BUILDING BLOCKS ; ENANTIOSELECTIVE ACETYLATION ; ENZYMATIC ACETYLATION ; FURANONES
Elenco autori:
P. Allevi, P. Ciuffreda, M. Anastasia
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