Data di Pubblicazione:
1983
Citazione:
Synthesis of C-2 and C-4 deuterium-labeled estradiol-17β / P. Ferraboschi, M. Ravasi, E. Santaniello. - In: STEROIDS. - ISSN 0039-128X. - 41:6(1983), pp. 777-782.
Abstract:
Estradiol-17β labeled with deuterium in the positions 2 or 4 can be prepared from 2-chloromercurio-1,3,5(10)-estratriene-3,17β-diol 3-methyl ether 17-acetate or 4-chloromercurio-1,3,5(10)-estratriene-3,17β -diol, respectively, in refluxing CH3COO2H/2H20. The same reaction performed on 4-acetoxymercurio-1,3,5(10)-estratriene-3,17β -diol afforded 2,4-dideuterio-estradiol-17β in good yields
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
P. Ferraboschi, M. Ravasi, E. Santaniello
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