Data di Pubblicazione:
1992
Citazione:
ROLE OF ENDOTHELIN-1 IN CARRAGEENAN-INDUCED INFLAMMATION / A. BERTELLI, A. CLERICO, A. CHICCA, L. GIOVANNINI, A. GORIO, M. ROMANO. - In: INTERNATIONAL JOURNAL OF TISSUE REACTIONS. - ISSN 0250-0868. - 14:5(1992), pp. 225-230.
Abstract:
Many vasal factors are produced during an experimental model of inflammation such as rat-paw oedema induced by carrageenin. We investigated whether among the other well-known mediators of inflammation, i.e. serotonin, PAF, eicosanoids and kinins, the peptide endothelin-1 is produced by this kind of inflammatory process caused by carrageenin. Our results indicated that plasma endothelin, and the tissue concentration of endothelin in the oedematous paw, is increased as compared to the control. Consequently, endothelin should also be considered as an important factor in inflammatory processes.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
A. BERTELLI, A. CLERICO, A. CHICCA, L. GIOVANNINI, A. GORIO, M. ROMANO
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