Evaluation of Azadirachta indica leaf extract for hypoglycaemic activity in rats

Water soluble fractions separated from the crude leaf extract of Azadirachta indica A. Juss. lowered hyperglycaemia in streptozotocin diabetes. Systematic fractionation of the concentrates led to the isolation of flavonol glycosides, quercetin-3-O-β-D-glucoside, myricetin-3-O-rutinoside, quercetin-3-O-rutinoside, kaempferol-3-O-rutinoside, kaempferol-3-O-β-D-glucoside and quercetin-3-O-α-L-rhamnoside.