Abnormalities of cyclic adenosine monophosphate signaling in platelets from untreated patients with bipolar disorder
Articolo
Data di Pubblicazione:
1999
Citazione:
Abnormalities of cyclic adenosine monophosphate signaling in platelets from untreated patients with bipolar disorder / J. Perez, D. Tardito, S. Mori, G. Racagni, E. Smeraldi, R. Zanardi. - In: ARCHIVES OF GENERAL PSYCHIATRY. - ISSN 0003-990X. - 56:3(1999 Mar), pp. 248-253.
Abstract:
Abnormalities in the cyclic adenosine monophosphate (cAMP)-dependent phosphorylation system have been recently reported in patients with bipolar disorder. We evaluated the immunoreactivity of the regulatory and catalytic subunits of cAMP-dependent protein kinase (protein kinase A) and 1 of its substrates, Rap1, in platelets from untreated euthymic, manic, and depressed patients with bipolar disorder and healthy subjects.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Bipolar disorder; platelets; Rap1; protein kinase A
Elenco autori:
J. Perez, D. Tardito, S. Mori, G. Racagni, E. Smeraldi, R. Zanardi
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