Synthesis of (24R)- and (24S)-24,28-epoxyergost-5-en-3β-ols. Substrate stereospecificity in their metabolism in the insect tenebrio molitor
Articolo
Data di Pubblicazione:
1984
Citazione:
Synthesis of (24R)- and (24S)-24,28-epoxyergost-5-en-3β-ols. Substrate stereospecificity in their metabolism in the insect tenebrio molitor / F. Nicotra, F. Ronchetti, G. Russo, L. Toma. - In: JOURNAL OF THE CHEMICAL SOCIETY. PERKIN TRANSACTIONS. I. - ISSN 0300-922X. - :0(1984), pp. 2039-2042. [10.1039/P19840002039]
Abstract:
(24R)- and (24S)-24,28-Epoxyergost-5-en-3β-ols have been synthesized and their configuration at C-24 assigned. When these 24,28-epoxides were tritium labelled and fed in separate experiments to Tenebrio molitor larvae, only the (24R) stereoisomer was effectively converted into cholesterol, indicating that in this step of phytosterol metabolism the insect exhibits a high degree of substrate stereospecificity.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
F. Nicotra, F. Ronchetti, G. Russo, L. Toma
Link alla scheda completa: