Early reduction in left ventricular contractile reserve detected by dobutamine stress echo predicts high-dose chemotherapy-induced cardiac toxicity
Articolo
Data di Pubblicazione:
2006
Citazione:
Early reduction in left ventricular contractile reserve detected by dobutamine stress echo predicts high-dose chemotherapy-induced cardiac toxicity / M. Civelli, D. Cardinale, A. Martinoni, G. Lamantia, N. Colombo, A. Colombo, S. Gandini, G. Martinelli, C. Fiorentini, C. M. Cipolla. - In: INTERNATIONAL JOURNAL OF CARDIOLOGY. - ISSN 0167-5273. - 111:1(2006 Jul 28), pp. 120-6-126.
Abstract:
High-dose chemotherapy (HDC) is utilized in high-risk cancer patients. This type of treatment may induce cardiac toxicity which becomes clinically evident weeks or months after HDC. Hence, the possibility of early identification of patients who will develop cardiac impairment is strategic for its clinical implications. The aim of this study was to identify possible early changes of left ventricular contractile reserve (LVCR) in cancer patients undergoing HDC, as well as to evaluate the relevance of such changes as predictors of chemotherapy-induced cardiotoxicity.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Heart Diseases; Echocardiography, Stress; Antineoplastic Agents; Cardiotonic Agents; Humans; Breast Neoplasms; Predictive Value of Tests; Dobutamine; Prospective Studies; Adult; Ventricular Dysfunction, Left; Time Factors; Female
Elenco autori:
M. Civelli, D. Cardinale, A. Martinoni, G. Lamantia, N. Colombo, A. Colombo, S. Gandini, G. Martinelli, C. Fiorentini, C. M. Cipolla
Link alla scheda completa: