Data di Pubblicazione:
1985
Citazione:
REACTION OF ALDOSES WITH AMINO-ACIDS AND PROTEINS .1. REACTION OF LYSINE WITH ALDOSES / G. CANDIANO, G. GHIGGERI, G. DELFINO, C. QUIEROLO, C. CUNIBERTI, E. GIANAZZA, P. RIGHETTI. - In: CARBOHYDRATE RESEARCH. - ISSN 0008-6215. - 145:1(1985), pp. 99-112. [10.1016/S0008-6215(00)90416-6]
Abstract:
The reactivity of amino acids with trioses and hexoses under physiological conditions (37°, pH 7.5) has been investigated. The most reactive species were lysine, glyceraldehyde, and 2-amino-2-deoxyglucose. They generated yellow, oligomeric compounds having molecular weights in the range 500-1000 and pI values in the range pH 4-6. In the Lys-glyceraldehyde adduct, the ε-amino group is incorporated into a pyrrole-type structure, which gives a positive reaction with the Pauly reagent. The largest oligomers correspond to the condensation of 4 mol of Lys with 8-10 mol of glyceraldehyde. It is hypothesised that the primary Amadori-compound rearranges during the Maillard reaction to give browning products, since no yellow oligomers are produced if the Lys-aldehyde adduct is reduced immediately with cyanoborohydride.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
G. Candiano, G. Ghiggeri, G. Delfino, C. Quierolo, C. Cuniberti, E. Gianazza, P. Righetti
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