Data di Pubblicazione:
2012
Citazione:
CLOSING-IN BEHAVIOUR IN MILD COGNITIVE IMPAIRMENT: UN DEFICIT ESECUTIVO / S. Finotto ; tutor: C. Mariani; coordinatore: E. Ambron ; supervisore: S. Della Sala. Universita' degli Studi di Milano, 2012 May 30. 24. ciclo, Anno Accademico 2011. [10.13130/finotto-sara_phd2012-05-30].
Abstract:
This study explored Closing-in behavior (CIB), the tendency in figure copying to draw very close to or on top of the
model, in mild cognitive impairment (MCI). The files of 154 people diagnosed with MCI were reviewed and CIB was
identified in 21% of cases. Two approaches were used to explore CIB. First, we capitalized on the diverse cognitive
profiles within MCI, subdividing the overall sample into people with and without memory deficits. The frequency of CIB
was significantly higher in multidomain non-amnestic MCI than in multidomain amnestic MCI, suggesting that CIB is not
associated with specific memory impairment. Second, we assessed the cognitive correlates of CIB, by selecting patients
with MCI who completed a battery of executive, visuo-constructional and memory tasks. Sub-groups of patients with and
without CIB showed a similar overall severity of cognitive decline and comparable performance in visuo-constructional
and memory tasks, but those with CIB were slightly but significantly more impaired on executive function tasks.
The study provides evidence against memory-based accounts of CIB, and supports recent suggestions that executive
impairments are the dominant cognitive correlate of this clinical sign.
Tipologia IRIS:
Tesi di dottorato
Elenco autori:
S. Finotto
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