Data di Pubblicazione:
2012
Citazione:
First report of reproductive assistance in a woman affected by May-Hegglin anomaly / V. Savasi, A. Laoreti, M. Elli, T. Brambilla, A. Federici, I. Cetin. - In: ARCHIVES OF GYNECOLOGY AND OBSTETRICS. - ISSN 0932-0067. - 285:3(2012 Mar), pp. 879-892. [10.1007/s00404-011-2117-1]
Abstract:
PURPOSE: To report the first case of fertility treatment in a patient with May-Hegglin anomaly, a rare hematological disorder inherited as an autosomal dominant trait.
METHOD: We present a case report of a 40-year-old nulliparous patient with May-Hegglin anomaly who underwent her first ICSI cycle with transfer of three fresh embryos.
RESULTS: Prophylactic platelet transfusion obtained by single-donor apheresis was performed 1 h before the oocyte pick up. No complications were reported. No pregnancy was obtained.
CONCLUSIONS: We report about the possibility to assist women affected by May-Hegglin anomaly requiring reproductive assistance. However, a multidisciplinary team composed of gynecologists and hematologists should follow such patients carefully, in order to carry out a complete clinical evaluation and to prevent the potential risks of bleeding. Clinicians must be vigilant in their presentation of risks, benefits, and alternatives.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
May-Hegglin anomaly; fertility treatment; ICSI; assisted reproductive techniques
Elenco autori:
V. Savasi, A. Laoreti, M. Elli, T. Brambilla, A. Federici, I. Cetin
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