Data di Pubblicazione:
1990
Citazione:
Antibodies to hepatitis C virus in blood donors / P. Ferroni, A. Tagger, M.L. Ribero, A. Grossi, F. Pregliasco, M.L. Pasquali, S. Salvaneschi. - In: EUROPEAN JOURNAL OF EPIDEMIOLOGY. - ISSN 0393-2990. - 6:3(1990 Sep), pp. 326-328.
Abstract:
Recently a recombinant polypeptide of hepatitis C virus (HCV) has been developed by the Chiron Corporation in California. This antigen has been used to develop an ELISA test (Ortho Diagnostic Systems for serum anti-HCV antibodies. Preliminary data have shown that this virus is the major cause of NANB hepatitis in the world. We examined differences in anti-HCV prevalence among subgroups of blood donors (total sera examined 639) classified for past or present exposure to HBV or not, and for ALT levels. The anti-HCV prevalence found in regular blood donors with normal ALT levels and no antibody to HBcAg was 1.2%. No significant difference in the anti-HCV prevalence was found among other subgroups of blood donors except that a higher prevalence (10%) was found in a group with both elevated ALT and HBV markers. These preliminary findings suggest that the policy of blood supply should take into account the advent of HCV antibody test.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Hepacivirus; Humans ; Hepatitis Antibodies ; Enzyme-Linked Immunosorbent Assay ; Hepatitis C ; Blood Donors ; Prevalence
Elenco autori:
P. Ferroni, A. Tagger, M.L. Ribero, A. Grossi, F. Pregliasco, M.L. Pasquali, S. Salvaneschi
Link alla scheda completa: