Effects of cytokinins, cytokinin ribosides and their analogs on the viability of normal and neoplastic human cells
Articolo
Data di Pubblicazione:
2011
Citazione:
Effects of cytokinins, cytokinin ribosides and their analogs on the viability of normal and neoplastic human cells / S. Casati, R. Ottria, E. Baldoli, E. Lopez, J.A. Maier, P. Ciuffreda. - In: ANTICANCER RESEARCH. - ISSN 0250-7005. - 31:10(2011 Oct), pp. 3401-3406.
Abstract:
We examined the effects of some cytokinins and cytokinin ribosides including a series of adenosine analogs differently substituted in the N(6) position, along with some hypoxanthine derivatives on the viability of normal and neoplastic human cells. Cytokinins such as trans-zeatin, isopentenyladenine and benzyladenine do not show any effect, while cytokinin ribosides such as trans-zeatin riboside, isopentenyladenosine, and benzylaminopurine riboside impair the viability of normal and neoplastic cells, apart from colon carcinoma LoVo cells.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Drug Screening Assays, Antitumor ; Cytokinins ; Humans ; Cell Line, Tumor ; Drug Resistance, Neoplasm ; Cell Survival ; Isopentenyladenosine ; Neoplasms ; Cisplatin ; Neutral Red ; Ribonucleosides ; Adenosine ; Tumor Stem Cell Assay ; Zeatin
Elenco autori:
S. Casati, R. Ottria, E. Baldoli, E. Lopez, J.A. Maier, P. Ciuffreda
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