Data di Pubblicazione:
2007
Citazione:
In vitro approaches to the assessment of immunotoxicity / E. Corsini, M. Carfì, L. Gribaldo, M. Pallardy, R. Pieters, R. Vandebriel, H.W. Vohr, H. Van Loveren. - In: TOXICOLOGY LETTERS. - ISSN 0378-4274. - 172:suppl. 1(2007), pp. S6-S7. ((Intervento presentato al 44. convegno Congress of the European Societies of Toxicology (EUROTOX) tenutosi a Amsterdam nel 2007 [10.1016/j.toxlet.2007.05.039].
Abstract:
At present, hypersensitivity and immunosuppression
are considered the primary focus for developing in vitro
methods in immunotoxicology. Nevertheless, in vitro
assays to detect immunostimulation and autoimmunity
are also needed. Although developmental immunotoxicity
is an emerging concern, there are no in vitro test
models available at this time.
The purpose of this presentation is to reviewthe stateof-
the-art in the field of in vitro immunotoxicity and, in
particular, to present data obtained within an ECVAM
sponsored project aimed at the optimization of in vitro
tests to assess the immunosuppressive potential of chemicals.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
cytokine release ; stimulation of lymphocyte proliferation
Elenco autori:
E. Corsini, M. Carfì, L. Gribaldo, M. Pallardy, R. Pieters, R. Vandebriel, H.W. Vohr, H. Van Loveren
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